Cyclin-dependent kinase 2
Kinase structure
Kinase:CDK2
Family:CDK
Group:CMGC
Species:HUMAN
IUPHAR/BPS ID:1973
PDB:6Q3C
sc-PDB:
KIDFamMap:Search
Release date:2019-03-20
PubMed: 30860382
Chain:A
(Alternate) Model:C
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The orthosteric binding pocket


More entries for 6Q3C
6Q3CAlternative model: AChain: A
6Q3CAlternative model: BChain: A


Structural information
DFG conformation:in
αC-helix conformation:out
G-rich loop angle (distance):51.8° (14.7Å)
G-rich loop rotation:68.8°
Quality Score:9
Resolution:1.29 Å
Missing Residues:1
Missing Atoms:6
Ligand binding mode
Waters
Cluster
I2
I3
I4
I5
I7
Ligand
No
No
No
No
No
Protein
No
Yes
No
Yes
Yes

Pocket alignment
Uniprot sequence:EKIGEGTYGVVYKVALKKITAIREISLLKELNPNIVKLLDVYLVFEFLH-QDLKKFMDAFCHSHRVLHRDLKPQNLLILADFGLA
Sequence structure:EKIGEGTYGVVYKVALKKITAIREISLLKELNPNIVKLLDVYLVFEFLH_QDLKKFMDAF_HSHRVLHRDLKPQNLLILADFGLA