PDB-code
Browse kinase entries (page 1 of 282)
Last5 4 3 Next| # | Kinase | Family | Group | PDB | Chain | (Alternate) Model | Orthosteric ligand | Organism | Details | File |
|---|---|---|---|---|---|---|---|---|---|---|
 | Aak1 (AAK1) | NAK | Other | 7lvh | A | n-[3-methoxy-4-(1,3-oxazol-5-yl)phenyl]-d-leucinamide | Mouse | Show |  | |
| Aak1 (AAK1) | NAK | Other | 7lvi | A | A | (2r,3r)-n-[3-methoxy-4-(1,3-oxazol-5-yl)phenyl]-3-(propan-2-yl)piperidine-2-carboxamide | Mouse | Show | |
| Aak1 (AAK1) | NAK | Other | 7lvi | A | B | (2r,3r)-n-[3-methoxy-4-(1,3-oxazol-5-yl)phenyl]-3-(propan-2-yl)piperidine-2-carboxamide | Mouse | Show | |
| Aak1 (AAK1) | NAK | Other | 7rj6 | A | A | 5-[(4-aminopiperidin-1-yl)methyl]-n-{3-[5-(propan-2-yl)-1,3,4-thiadiazol-2-yl]phenyl}pyrrolo[2,1-f][1,2,4]triazin-4-amine | Mouse | Show | |
| Aak1 (AAK1) | NAK | Other | 7rj6 | A | B | 5-[(4-aminopiperidin-1-yl)methyl]-n-{3-[5-(propan-2-yl)-1,3,4-thiadiazol-2-yl]phenyl}pyrrolo[2,1-f][1,2,4]triazin-4-amine | Mouse | Show | |
| Aak1 (AAK1) | NAK | Other | 7rj7 | A | A | 2-[(1s)-1-amino-3-methylbutyl]-6-(pyridin-4-yl)quinoline-4-carbonitrile | Mouse | Show | |
| Aak1 (AAK1) | NAK | Other | 7rj7 | A | B | 2-[(1s)-1-amino-3-methylbutyl]-6-(pyridin-4-yl)quinoline-4-carbonitrile | Mouse | Show | |
| Aak1 (AAK1) | NAK | Other | 7rj8 | A | A | n-[3-(difluoromethoxy)-4-(1,3-oxazol-5-yl)phenyl]-d-leucinamide | Mouse | Show | |
| Aak1 (AAK1) | NAK | Other | 7rj8 | A | B | n-[3-(difluoromethoxy)-4-(1,3-oxazol-5-yl)phenyl]-d-leucinamide | Mouse | Show | |
| AAK1 | NAK | Other | 4wsq | A | A | k-252a | Human | Show | |
| AAK1 | NAK | Other | 4wsq | A | B | k-252a | Human | Show | |
| AAK1 | NAK | Other | 4wsq | B | A | k-252a | Human | Show | |
| AAK1 | NAK | Other | 4wsq | B | B | k-252a | Human | Show | |
| AAK1 | NAK | Other | 5l4q | A | A | ~{n}-[5-(4-cyanophenyl)-1~{h}-pyrrolo[2,3-b]pyridin-3-yl]pyridine-3-carboxamide | Human | Show | |
| AAK1 | NAK | Other | 5l4q | A | B | ~{n}-[5-(4-cyanophenyl)-1~{h}-pyrrolo[2,3-b]pyridin-3-yl]pyridine-3-carboxamide | Human | Show | |
| AAK1 | NAK | Other | 5l4q | B | A | ~{n}-[5-(4-cyanophenyl)-1~{h}-pyrrolo[2,3-b]pyridin-3-yl]pyridine-3-carboxamide | Human | Show | |
| AAK1 | NAK | Other | 5l4q | B | B | ~{n}-[5-(4-cyanophenyl)-1~{h}-pyrrolo[2,3-b]pyridin-3-yl]pyridine-3-carboxamide | Human | Show | |
| AAK1 | NAK | Other | 5te0 | A | methyl (3z)-3-{[(4-{methyl[(4-methylpiperazin-1-yl)acetyl]amino}phenyl)amino](phenyl)methylidene}-2-oxo-2,3-dihydro-1h-indole-6-carboxylate | Human | Show | | |
| AAK1 | NAK | Other | 8gmc | A | 5-[(4-aminopiperidin-1-yl)methyl]-n-{3-[5-(propan-2-yl)-1,3,4-thiadiazol-2-yl]phenyl}pyrrolo[2,1-f][1,2,4]triazin-4-amine | Human | Show | | |
| AAK1 | NAK | Other | 8gmd | A | (5p)-3-({(8r)-5-[(4-aminopiperidin-1-yl)methyl]pyrrolo[2,1-f][1,2,4]triazin-4-yl}amino)-5-[2-(propan-2-yl)-2h-tetrazol-5-yl]phenol | Human | Show | | |
| Abl1 (ABL1) | Abl | TK | 1fpu | A | n-[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]-3-pyridinecarboxamide | Mouse | Show | | |
| Abl1 (ABL1) | Abl | TK | 1fpu | B | n-[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]-3-pyridinecarboxamide | Mouse | Show | | |
| Abl1 (ABL1) | Abl | TK | 1iep | A | 4-(4-methyl-piperazin-1-ylmethyl)-n-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-benzamide | Mouse | Show | | |
| Abl1 (ABL1) | Abl | TK | 1iep | B | 4-(4-methyl-piperazin-1-ylmethyl)-n-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-benzamide | Mouse | Show | | |
| Abl1 (ABL1) | Abl | TK | 1m52 | A | 6-(2,6-dichloro-phenyl)-8-methyl-2-(3-methylsulfanyl-phenylamino)-8h-pyrido[2,3-d]pyrimidin-7-one | Mouse | Show | | |
| Abl1 (ABL1) | Abl | TK | 1m52 | B | 6-(2,6-dichloro-phenyl)-8-methyl-2-(3-methylsulfanyl-phenylamino)-8h-pyrido[2,3-d]pyrimidin-7-one | Mouse | Show | | |
| Abl1 (ABL1) | Abl | TK | 1opj | A | 4-(4-methyl-piperazin-1-ylmethyl)-n-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-benzamide | Mouse | Show | | |
| Abl1 (ABL1) | Abl | TK | 1opj | B | 4-(4-methyl-piperazin-1-ylmethyl)-n-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-benzamide | Mouse | Show | | |
| Abl1 (ABL1) | Abl | TK | 1opk | A | 6-(2,6-dichlorophenyl)-2-{[3-(hydroxymethyl)phenyl]amino}-8-methylpyrido[2,3-d]pyrimidin-7(8h)-one | Mouse | Show | | |
| Abl1 (ABL1) | Abl | TK | 2hzn | A | 1-[4-(pyridin-4-yloxy)phenyl]-3-[3-(trifluoromethyl)phenyl]urea | Mouse | Show | | |
| Abl1 (ABL1) | Abl | TK | 2qoh | A | 5-[3-(2-methoxyphenyl)-1h-pyrrolo[2,3-b]pyridin-5-yl]-n,n-dimethylpyridine-3-carboxamide | Mouse | Show | | |
| Abl1 (ABL1) | Abl | TK | 2qoh | B | 5-[3-(2-methoxyphenyl)-1h-pyrrolo[2,3-b]pyridin-5-yl]-n,n-dimethylpyridine-3-carboxamide | Mouse | Show | | |
| Abl1 (ABL1) | Abl | TK | 2z60 | A | 5-[3-(2-methoxyphenyl)-1h-pyrrolo[2,3-b]pyridin-5-yl]-n,n-dimethylpyridine-3-carboxamide | Mouse | Show | | |
| Abl1 (ABL1) | Abl | TK | 3dk3 | A | A | 2-amino-5-[3-(1-ethyl-1h-pyrazol-5-yl)-1h-pyrrolo[2,3-b]pyridin-5-yl]-n,n-dimethylbenzamide | Mouse | Show | |
| Abl1 (ABL1) | Abl | TK | 3dk3 | A | B | 2-amino-5-[3-(1-ethyl-1h-pyrazol-5-yl)-1h-pyrrolo[2,3-b]pyridin-5-yl]-n,n-dimethylbenzamide | Mouse | Show | |
| Abl1 (ABL1) | Abl | TK | 3dk3 | B | A | 2-amino-5-[3-(1-ethyl-1h-pyrazol-5-yl)-1h-pyrrolo[2,3-b]pyridin-5-yl]-n,n-dimethylbenzamide | Mouse | Show | |
| Abl1 (ABL1) | Abl | TK | 3dk3 | B | B | 2-amino-5-[3-(1-ethyl-1h-pyrazol-5-yl)-1h-pyrrolo[2,3-b]pyridin-5-yl]-n,n-dimethylbenzamide | Mouse | Show | |
| Abl1 (ABL1) | Abl | TK | 3dk6 | A | 2-amino-5-[3-(1-ethyl-1h-pyrazol-5-yl)-1h-pyrrolo[2,3-b]pyridin-5-yl]-n,n-dimethylbenzamide | Mouse | Show | | |
| Abl1 (ABL1) | Abl | TK | 3dk6 | B | 2-amino-5-[3-(1-ethyl-1h-pyrazol-5-yl)-1h-pyrrolo[2,3-b]pyridin-5-yl]-n,n-dimethylbenzamide | Mouse | Show | | |
| Abl1 (ABL1) | Abl | TK | 3dk7 | A | 2-amino-5-[3-(1-ethyl-1h-pyrazol-5-yl)-1h-pyrrolo[2,3-b]pyridin-5-yl]-n,n-dimethylbenzamide | Mouse | Show | | |
| Abl1 (ABL1) | Abl | TK | 3dk7 | B | 2-amino-5-[3-(1-ethyl-1h-pyrazol-5-yl)-1h-pyrrolo[2,3-b]pyridin-5-yl]-n,n-dimethylbenzamide | Mouse | Show | | |
| Abl1 (ABL1) | Abl | TK | 3ik3 | A | 3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-n-{4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}benzamide | Mouse | Show | | |
| Abl1 (ABL1) | Abl | TK | 3ik3 | B | 3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-n-{4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}benzamide | Mouse | Show | | |
| Abl1 (ABL1) | Abl | TK | 3k5v | A | A | 4-(4-methyl-piperazin-1-ylmethyl)-n-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-benzamide | Mouse | Show | |
| Abl1 (ABL1) | Abl | TK | 3k5v | A | B | 4-(4-methyl-piperazin-1-ylmethyl)-n-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-benzamide | Mouse | Show | |
| Abl1 (ABL1) | Abl | TK | 3k5v | B | A | 4-(4-methyl-piperazin-1-ylmethyl)-n-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-benzamide | Mouse | Show | |
| Abl1 (ABL1) | Abl | TK | 3k5v | B | B | 4-(4-methyl-piperazin-1-ylmethyl)-n-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-benzamide | Mouse | Show | |
| Abl1 (ABL1) | Abl | TK | 3kf4 | A | n-[4-(dimethylphosphoryl)phenyl]-9-[(e)-2-(5-methyl-1h-indazol-4-yl)ethenyl]-9h-purin-6-amine | Mouse | Show | | |
| Abl1 (ABL1) | Abl | TK | 3kf4 | B | n-[4-(dimethylphosphoryl)phenyl]-9-[(e)-2-(5-methyl-1h-indazol-4-yl)ethenyl]-9h-purin-6-amine | Mouse | Show | | |
| Abl1 (ABL1) | Abl | TK | 3kfa | A | 3-{(e)-2-[6-(cyclopropylamino)-9h-purin-9-yl]ethenyl}-4-methyl-n-[3-(4-methyl-1h-imidazol-1-yl)-5-(trifluoromethyl)phenyl]benzamide | Mouse | Show | |
