Cyclin-dependent kinase 2
Kinase structure
Kinase:CDK2
Family:CDK
Group:CMGC
Species:HUMAN
IUPHAR/BPS ID:1973
PDB:6Q49
sc-PDB:
KIDFamMap:Search
Release date:2019-03-20
PubMed: 30860382
Chain:A
(Alternate) Model:A
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The orthosteric binding pocket


More entries for 6Q49
6Q49Alternative model: BChain: A
6Q49Alternative model: CChain: A


Structural information
DFG conformation:in
αC-helix conformation:out
G-rich loop angle (distance):49.3° (14.1Å)
G-rich loop rotation:63.9°
Quality Score:8
Resolution:1 Å
Missing Residues:0
Missing Atoms:0
Ligand binding mode
Waters
Cluster
I2
I4
I5
I6
Ligand
No
No
No
No
Protein
No
No
No
Yes

Allosteric Ligand
Allosteric ligand:HGQ
2D structure of the allostericligand
Pocket alignment
Uniprot sequence:EKIGEGTYGVVYKVALKKITAIREISLLKELNPNIVKLLDVYLVFEFLH-QDLKKFMDAFCHSHRVLHRDLKPQNLLILADFGLA
Sequence structure:EKIGEGTYGVVYKVALKKITAIREISLLKELNPNIVKLLDVYLVFEFLH_QDLKKFMDAFCHSHRVLHRDLKPQNLLILADFGLA