Version: 3.2
Updated: 29-Oct-2025
Protein kinase, cAMP dependent, catalytic, alpha
Kinase structure
Kinase:Prkaca (PKACa)
Family:PKA
Group:AGC
Species:MOUSE
PDB:6MM8
sc-PDB:
KIDFamMap:Search
Release date:2019-05-08
Chain:C
(Alternate) Model:A
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The orthosteric binding pocket


More entries for 6MM8
6MM8Alternative model: BChain: C
6MM8Alternative model: CChain: C


Structural information
DFG conformation:in
αC-helix conformation:in
G-rich loop angle (distance):66.4° (21.3Å)
G-rich loop rotation:70.6°
Quality Score:9.2
Resolution:1.85 Å
Missing Residues:0
Missing Atoms:8
Ligand binding mode
Waters
Cluster
I3
I10
Ligand
No
No
Protein
Yes
Yes

Pocket alignment
Uniprot sequence:KTLGTGSFGRVMLYAMKILHTLNEKRILQAVNPFLVKLEFSYMVMEYVAGGEMFSHLRRYLHSLDLIYRDLKPENLLIVTDFGFA
Sequence structure:KTLGTGSFGRVMLYAMKILHTLNEKRILQAVNPFLVKLEFSYMVMEYVAGGEMFSHLRRYLHSLDLIYRDLKPENLLIVTDFGFA