Version: 3.2
Updated: 29-Oct-2025
Protein kinase, cAMP dependent, catalytic, alpha
Kinase structure
Kinase:Prkaca (PKACa)
Family:PKA
Group:AGC
Species:MOUSE
PDB:6MM5
sc-PDB:
KIDFamMap:Search
Release date:2019-05-08
Chain:E
(Alternate) Model:A
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The orthosteric binding pocket


More entries for 6MM5
6MM5Alternative model: BChain: E


Structural information
DFG conformation:in
αC-helix conformation:in
G-rich loop angle (distance):55.9° (17.3Å)
G-rich loop rotation:79.1°
Quality Score:8
Resolution:1.95 Å
Missing Residues:0
Missing Atoms:0
Ligand binding mode
Waters
Cluster
I1
I4
I5
I11
Ligand
No
No
No
No
Protein
Yes
Yes
Yes
Yes

Pocket alignment
Uniprot sequence:KTLGTGSFGRVMLYAMKILHTLNEKRILQAVNPFLVKLEFSYMVMEYVAGGEMFSHLRRYLHSLDLIYRDLKPENLLIVTDFGFA
Sequence structure:KTLGTGSFGRVMLYAMKILHTLNEKRILQAVNPFLVKLEFSYMVMEYVAGGEMFSHLRRYLHSLDLIYRDLKPENLLIVTDFGFA