Version: 3.2
Updated: 05-Nov-2025
Death-associated protein kinase 2
Kinase structure
Kinase:DAPK2
Family:DAPK
Group:CAMK
Species:HUMAN
IUPHAR/BPS ID:2003
PDB:2A27
sc-PDB:
KIDFamMap:Search
Release date:2006-10-10
Chain:E
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The orthosteric binding pocket


More entries for 2A27
2A27Chain: A
2A27Chain: B
2A27Chain: C
2A27Chain: D
2A27Chain: F
2A27Chain: G
2A27Chain: H


Structural information
DFG conformation:in
αC-helix conformation:in
G-rich loop angle (distance):55.2° (16.4Å)
G-rich loop rotation:41°
Quality Score:8
Resolution:3 Å
Missing Residues:0
Missing Atoms:0
Ligand binding mode
Waters
Cluster
I5
Ligand
No
Protein
Yes

Pocket alignment
Uniprot sequence:EELGSGQFAIVKKYAAKFIEIEREVSILRQVLHNVITLHDVVLILELVSGGELFDFLAQYLHTKKIAHFDLKPENIMLLIDFGLA
Sequence structure:EELGSGQFAIVKKYAAKFIEIEREVSILRQVLHNVITLHDVVLILELVSGGELFDFLAQYLHTKKIAHFDLKPENIMLLIDFGLA