SRSF protein kinase 1
Kinase structure
Kinase:SRPK1
Family:SRPK
Group:CMGC
Species:HUMAN
IUPHAR/BPS ID:2208
PDB:6FAD
sc-PDB:
KIDFamMap:Search
Release date:2019-09-25
PubMed: 31641093
Chain:D
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The orthosteric binding pocket


More entries for 6FAD
6FADChain: A
6FADChain: B
6FADChain: C


Structural information
DFG conformation:in
αC-helix conformation:in
G-rich loop angle (distance):65.3° (19.8Å)
G-rich loop rotation:42.7°
Quality Score:8
Resolution:2.8 Å
Missing Residues:0
Missing Atoms:0
Ligand binding mode
Waters
Cluster
I1
I4
I5
Ligand
No
No
No
Protein
Yes
Yes
Yes

Pocket alignment
Uniprot sequence:RKLGWGHFSTVWLVAMKVVTALDEIRLLKSVREMVVQLLDDCMVFEVLG-HHLLKWIIKLHTKCRIIHTDIKPENILLIADLGNA
Sequence structure:RKLGWGHFSTVWLVAMKVVTALDEIRLLKSVREMVVQLLDDCMVFEVLG_HHLLKWIIKLHTKCRIIHTDIKPENILLIADLGNA