Mitogen-activated protein kinase 12
Kinase structure
Kinase:MAPK12 (p38g)
Family:MAPK
Group:CMGC
Species:HUMAN
IUPHAR/BPS ID:1501
PDB:6UNA
sc-PDB:
KIDFamMap:Search
Release date:2019-12-18
PubMed: 31794659
Chain:A
(Alternate) Model:B
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The orthosteric binding pocket


More entries for 6UNA
6UNAAlternative model: AChain: A
6UNAAlternative model: AChain: B
6UNAAlternative model: BChain: B


Structural information
DFG conformation:in
αC-helix conformation:in
G-rich loop angle (distance):58.1° (17.6Å)
G-rich loop rotation:51°
Quality Score:8
Resolution:2.55 Å
Missing Residues:0
Missing Atoms:0

Pocket alignment
Uniprot sequence:QPVGSGAYGAVCSVAIKKLRAYRELRLLKHMRENVIGLLDVYLVMPFMG-TDLGKLMKHYIHAAGIIHRDLKPGNLAVILDFGLA
Sequence structure:RPVGSGAYGAVCSVAIKKLRAYRELRLLKHMRENVIGLLDVYLVMPFMG_TDLGKLMKHYIHAAGIIHRDLKPGNLAVILDFGLA