Cyclin-dependent kinase 2
Kinase structure
Kinase:CDK2
Family:CDK
Group:CMGC
Species:HUMAN
IUPHAR/BPS ID:1973
PDB:6YL6
sc-PDB:
KIDFamMap:Search
Release date:2020-07-22
PubMed: 32659037
Chain:A
(Alternate) Model:A
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The orthosteric binding pocket


More entries for 6YL6
6YL6Alternative model: BChain: A


Structural information
DFG conformation:in
αC-helix conformation:out
G-rich loop angle (distance):50.1° (14.2Å)
G-rich loop rotation:68.5°
Quality Score:8
Resolution:1.7 Å
Missing Residues:0
Missing Atoms:0
Ligand binding mode
Waters
Cluster
I4
I7
Ligand
No
No
Protein
Yes
Yes

Pocket alignment
Uniprot sequence:EKIGEGTYGVVYKVALKKITAIREISLLKELNPNIVKLLDVYLVFEFLH-QDLKKFMDAFCHSHRVLHRDLKPQNLLILADFGLA
Sequence structure:EKIGEGTYGVVYKVALKKITAIREISLLKELNPNIVKLLDVYLVCEFLH_QDLKKFMDAFCHSHRVLHRDLKPQNLLILADFGLA