Interleukin 1 receptor associated kinase 3
Kinase structure
Kinase:IRAK3
Family:IRAK
Group:TKL
Species:HUMAN
IUPHAR/BPS ID:2044
PDB:6RUU
sc-PDB:
KIDFamMap:Search
Release date:2020-09-08
PubMed: 33238146
Chain:A
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The orthosteric binding pocket


More entries for 6RUU
6RUUChain: B
6RUUChain: C


Structural information
DFG conformation:in
αC-helix conformation:in
G-rich loop angle (distance):48.9° (14.9Å)
G-rich loop rotation:53.9°
Quality Score:8.6
Resolution:2.95 Å
Missing Residues:0
Missing Atoms:14

Pocket alignment
Uniprot sequence:FLIGEGEIFEVYRYAVKLFRFLSELEVLLLFHPNILELAAYCLIYPYMRNGTLFDRLQCNVQPCSVICGSISSANILLLTDFAMA
Sequence structure:FLIGEGEIFEVYRYAVKLFRFLSELEVLLLFHPNILELAAYCLIYPYMRNGTLFDRLQCNVQPCSVICGSISSANILLLTDFAMA