PDB-code
| Kinase structure | |
| Kinase: | JAK1 |
| Family: | JakA |
| Group: | TK |
| Species: | HUMAN |
| IUPHAR/BPS ID: | 2047 |
| PDB: | 4E4L |
| sc-PDB: | |
| KIDFamMap: | Search |
| Release date: | 2012-05-30 |
| PubMed: | 22591402 |
| Chain: | E |
| (Alternate) Model: | B |
| More entries for 4E4L | |||||
| 4E4L | Alternative model: | A | Chain: | A | |
| 4E4L | Alternative model: | A | Chain: | B | |
| 4E4L | Alternative model: | A | Chain: | D | |
| 4E4L | Alternative model: | A | Chain: | E | |
| 4E4L | Alternative model: | B | Chain: | A | |
| 4E4L | Alternative model: | B | Chain: | B | |
| 4E4L | Alternative model: | B | Chain: | D | |
| Structural information | |
| DFG conformation: | in |
| αC-helix conformation: | in |
| G-rich loop angle (distance): | 47.6° (14.7Å) |
| G-rich loop rotation: | 58° |
| Quality Score: | 8 |
| Resolution: | 2 Å |
| Missing Residues: | 0 |
| Missing Atoms: | 0 |
| Ligand binding mode | ||||
| Waters | ||||
| Cluster I4 I5 I7 I11 | Ligand No No No No | Protein Yes No Yes No | ||
| Pocket alignment | |
| Uniprot sequence: | RDLGEGHFGKVELVAVKSLDLKKEIEILRNLYENIVKYKGIKLIMEFLPSGSLKEYLPKYLGSRQYVHRDLAARNVLVIGDFGLT |
| Sequence structure: | RDLGEGHFGKVELVAVKSLDLKKEIEILRNLYENIVKYKGIKLIMEFLPSGSLKEYLPKYLGSRQYVHRDLAARNVLVIGDFGLT |
