Platelet derived growth factor receptor alpha
Kinase structure
Kinase:PDGFRA (PDGFRa)
Family:PDGFR
Group:TK
Species:HUMAN
IUPHAR/BPS ID:1803
PDB:8PQJ
sc-PDB:
KIDFamMap:Search
Release date:2023-12-27
PubMed: 38167404
Chain:A
(Alternate) Model:A
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The orthosteric binding pocket


More entries for 8PQJ
8PQJAlternative model: BChain: A


Structural information
DFG conformation:out
αC-helix conformation:in
G-rich loop angle (distance):62.5° (19Å)
G-rich loop rotation:46.5°
Quality Score:7.2
Resolution:1.82 Å
Missing Residues:0
Missing Atoms:0
Ligand binding mode
Waters
Cluster
I5
I6
Ligand
No
No
Protein
Yes
Yes

Pocket alignment
Uniprot sequence:RVLGSGAFGKVVEVAVKMLALMSELKIMTHLGLNIVNLLGAYIITEYCFYGDLVNYLHKFLASKNCVHRDLAARNVLLICDFGLA
Sequence structure:RVLGSGAFGKVVEVAVKMLALMSELKIMTHLGLNIVNLLGAYIITEYCFYGDLVNYLHKFLASKNCVHRDLAARNVLLICDFGLA