WNK lysine deficient protein kinase 3
Kinase structure
Kinase:WNK3 (Wnk3)
Family:WNK
Group:Other
Species:HUMAN
IUPHAR/BPS ID:2282
PDB:9D7Q
sc-PDB:
KIDFamMap:Search
Release date:2024-12-11
PubMed: 39584807
Chain:A
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The orthosteric binding pocket
Structural information
DFG conformation:in
αC-helix conformation:out
G-rich loop angle (distance):56.5° (16.1Å)
G-rich loop rotation:36.6°
Quality Score:9.4
Resolution:3.301 Å
Missing Residues:0
Missing Atoms:6
Ligand binding mode
Waters
Cluster
I1
I11
Ligand
No
No
Protein
No
Yes

Pocket alignment
Uniprot sequence:IELGRGAFKTVYKVAWCELRFKEEAEMLKGLQPNIVRFYDSVLVTELMTSGTLKTYLKRHTRTPPIIHRDLKCDNIFIIGDLGLA
Sequence structure:IELGRGAFKTVYKVAWCELRFKEEAEMLKGLQPNIVRFYDSVLVTELMTSGTLKTYLKRHTRTPPIIHRDLKCNNIFIIGDLGLA