Protein tyrosine kinase 2
Kinase structure
Kinase:PTK2 (FAK)
Family:FAK
Group:TK
Species:HUMAN
IUPHAR/BPS ID:2180
PDB:4EBW
sc-PDB:
KIDFamMap:Search
Release date:2012-07-25
PubMed: 22819505
Chain:A
(Alternate) Model:A
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The orthosteric binding pocket


More entries for 4EBW
4EBWAlternative model: BChain: A
4EBWAlternative model: CChain: A


Structural information
DFG conformation:out
αC-helix conformation:in
G-rich loop angle (distance):40.2° (13.7Å)
G-rich loop rotation:128.2°
Quality Score:4
Resolution:2.65 Å
Missing Residues:3
Missing Atoms:0
Ligand binding mode
Waters
Cluster
I4
Ligand
No
Protein
Yes

Allosteric Ligand
Allosteric ligand:0PF
2D structure of the allostericligand
Pocket alignment
Uniprot sequence:RCIGEGQFGDVHQVAIKTCKFLQEALTMRQFDPHIVKLIGVWIIMELCTLGELRSFLQVYLESKRFVHRDIAARNVLVLGDFGLS
Sequence structure:RCIGEGQFGDVHQVAIKTCKFLQEALTMRQFDPHIVKLIGVWIIMELCTGELR__SFLQYLESKRFVHRDIAARNVLVLGDFGL_