PDB-code
| Kinase structure | |
| Kinase: | PTK2 (FAK) |
| Family: | FAK |
| Group: | TK |
| Species: | HUMAN |
| IUPHAR/BPS ID: | 2180 |
| PDB: | 4EBV |
| sc-PDB: | |
| KIDFamMap: | Search |
| Release date: | 2012-08-22 |
| PubMed: | 22819505 |
| Chain: | A |
| (Alternate) Model: | C |
| More entries for 4EBV | |||||
| 4EBV | Alternative model: | A | Chain: | A | |
| 4EBV | Alternative model: | B | Chain: | A | |
| Structural information | |
| DFG conformation: | out-like |
| αC-helix conformation: | in |
| G-rich loop angle (distance): | 39.1° (13.2Å) |
| G-rich loop rotation: | 129.5° |
| Quality Score: | 4.9 |
| Resolution: | 1.67 Å |
| Missing Residues: | 3 |
| Missing Atoms: | 11 |
| Ligand binding mode | ||||
| Waters | ||||
| Cluster I4 I8 | Ligand No No | Protein Yes Yes | ||
| Allosteric Ligand | |
| Allosteric ligand: | 0O7 |
 | |
| Pocket alignment | |
| Uniprot sequence: | RCIGEGQFGDVHQVAIKTCKFLQEALTMRQFDPHIVKLIGVWIIMELCTLGELRSFLQVYLESKRFVHRDIAARNVLVLGDFGLS |
| Sequence structure: | RCIGEGQFGDVHQVAIKTCKFLQEALTMRQFDPHIVKLIGVWIIMELCTGELR__SFLQYLESKRFVHRDIAARNVLVLGDFGL_ |
