Protein tyrosine kinase 2
Kinase structure
Kinase:PTK2 (FAK)
Family:FAK
Group:TK
Species:HUMAN
IUPHAR/BPS ID:2180
PDB:4I4F
sc-PDB:
KIDFamMap:Search
Release date:2013-02-06
PubMed: 23414845
Chain:A
(Alternate) Model:A
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The orthosteric binding pocket


More entries for 4I4F
4I4FAlternative model: BChain: A
4I4FAlternative model: CChain: A


Structural information
DFG conformation:out
αC-helix conformation:in
G-rich loop angle (distance):39.1° (13.3Å)
G-rich loop rotation:124.9°
Quality Score:4
Resolution:1.75 Å
Missing Residues:3
Missing Atoms:0
Ligand binding mode
Waters
Cluster
I4
I8
O1
Ligand
No
No
No
Protein
Yes
Yes
Yes

Allosteric Ligand
Allosteric ligand:1BR
2D structure of the allostericligand
Pocket alignment
Uniprot sequence:RCIGEGQFGDVHQVAIKTCKFLQEALTMRQFDPHIVKLIGVWIIMELCTLGELRSFLQVYLESKRFVHRDIAARNVLVLGDFGLS
Sequence structure:RCIGEGQFGDVHQVAIKTCKFLQEALTMRQFDPHIVKLIGVWIIMELCTGELR__SFLQYLESKRFVHRDIAARNVLVLGDFGL_