Pim-1 proto-oncogene, serine/threonine kinase
Kinase structure
Kinase:PIM1
Family:PIM
Group:CAMK
Species:HUMAN
IUPHAR/BPS ID:2158
PDB:1YWV
sc-PDB:
KIDFamMap:Search
Release date:2005-04-26
PubMed: 15808862
Chain:A
(Alternate) Model:B
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The orthosteric binding pocket


More entries for 1YWV
1YWVAlternative model: AChain: A


Structural information
DFG conformation:in
αC-helix conformation:in
G-rich loop angle (distance):53.7° (16.5Å)
G-rich loop rotation:40.8°
Quality Score:8
Resolution:2 Å
Missing Residues:0
Missing Atoms:0
Ligand binding mode
Waters
Cluster
I2
I4
I5
I8
Ligand
No
No
No
No
Protein
No
Yes
Yes
No

Pocket alignment
Uniprot sequence:PLLGSGGFGSVYSVAIKHVRVPMEVVLLKKVSSGVIRLLDWVLILERPEVQDLFDFITEHCHNCGVLHRDIKDENILILIDFGSG
Sequence structure:PLLGSGGFGSVYSVAIKHVRVPMEVVLLKKVSSGVIRLLDWVLILERPEVQDLFDFITEHCHNCGVLHRDIKDENILILIDFGSG