PDB-code
| Kinase structure | |
| Kinase: | MAPK1 (Erk2) |
| Family: | MAPK |
| Group: | CMGC |
| Species: | HUMAN |
| IUPHAR/BPS ID: | 1495 |
| PDB: | 4IZA |
| sc-PDB: | |
| KIDFamMap: | Search |
| Release date: | 2013-04-10 |
| PubMed: | 23575685 |
| Chain: | A |
| (Alternate) Model: | A |
| More entries for 4IZA | |||||
| 4IZA | Alternative model: | A | Chain: | C | |
| 4IZA | Alternative model: | B | Chain: | A | |
| 4IZA | Alternative model: | B | Chain: | C | |
| Structural information | |
| DFG conformation: | in |
| αC-helix conformation: | in |
| G-rich loop angle (distance): | 59.7° (18.3Å) |
| G-rich loop rotation: | 45.1° |
| Quality Score: | 8.7 |
| Resolution: | 1.93 Å |
| Missing Residues: | 0 |
| Missing Atoms: | 13 |
| Ligand binding mode | ||||
| Waters | ||||
| Cluster I1 I3 I5 I10 | Ligand No No No No | Protein Yes No Yes No | ||
| Pocket alignment | |
| Uniprot sequence: | SYIGEGAYGMVCSVAIKKIRTLREIKILLRFRENIIGINDIYIVQDLME-TDLYKLLKTYIHSANVLHRDLKPSNLLLICDFGLA |
| Sequence structure: | SYIGEGAYGMVCSVAIKKIRTLREIKILLRFRENIIGINDIYIVQDLME_TDLYKLLKTYIHSANVLHRDLKPSNLLLICDFGLA |
