Bruton tyrosine kinase
Kinase structure
Kinase:BTK
Family:Tec
Group:TK
Species:HUMAN
IUPHAR/BPS ID:1948
PDB:3P08
sc-PDB:
KIDFamMap:Search
Release date:2010-11-03
Chain:B
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The orthosteric binding pocket


More entries for 3P08
3P08Chain: A


Structural information
DFG conformation:in
αC-helix conformation:out
G-rich loop angle (distance):66.1° (18.7Å)
G-rich loop rotation:63.6°
Quality Score:7.6
Resolution:2.3 Å
Missing Residues:0
Missing Atoms:0
Ligand binding mode
Waters
Cluster
I5
I6
I10
Ligand
No
No
No
Protein
Yes
No
Yes

Pocket alignment
Uniprot sequence:KELGTGQFGVVKYVAIKMIEFIEEAKVMMNLSEKLVQLYGVFIITEYMANGCLLNYLREYLESKQFLHRDLAARNCLVVSDFGLS
Sequence structure:KELGTGQFGVVKYVAIKMIEFIEEAKVMMNLSEKLVQLYGVFIITEYMANGCLLNYLREYLESKQFLHRDLAARNCLVVSDFGLS