Mitogen-activated protein kinase 13
Kinase structure
Kinase:MAPK13 (p38d)
Family:MAPK
Group:CMGC
Species:HUMAN
IUPHAR/BPS ID:1502
PDB:3COI
sc-PDB:
KIDFamMap:Search
Release date:2008-04-15
Chain:A
(Alternate) Model:A
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The orthosteric binding pocket


More entries for 3COI
3COIAlternative model: BChain: A


Structural information
DFG conformation:in
αC-helix conformation:in
G-rich loop angle (distance):56.8° (17.3Å)
G-rich loop rotation:50.8°
Quality Score:9.3
Resolution:2.09 Å
Missing Residues:0
Missing Atoms:7
Ligand binding mode
Waters
Cluster
I4
I5
I8
I11
Ligand
No
No
No
No
Protein
Yes
Yes
Yes
Yes

Pocket alignment
Uniprot sequence:THVGSGAYGSVCSVAIKKLRAYRELLLLKHMQENVIGLLDVYLVMPFMQ-TDLQKIMGMYIHSAGVVHRDLKPGNLAVILDFGLA
Sequence structure:THVGSGAYGSVCSVAIKKLRAYRELLLLKHMQENVIGLLDVYLVMPFMQ_TDLQKIMGLYIHSAGVVHRDLKPGNLAVILDFGLA