Protein kinase C iota
Kinase structure
Kinase:PRKCI (PKCi)
Family:PKC
Group:AGC
Species:HUMAN
IUPHAR/BPS ID:1490
PDB:3A8X
sc-PDB:
KIDFamMap:Search
Release date:2010-05-05
PubMed: 20445233
Chain:B
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The orthosteric binding pocket


More entries for 3A8X
3A8XChain: A


Structural information
DFG conformation:in
αC-helix conformation:in
G-rich loop angle (distance):56.3° (16.7Å)
G-rich loop rotation:53.9°
Quality Score:8
Resolution:2 Å
Missing Residues:0
Missing Atoms:0
Ligand binding mode
Waters
Cluster
I2
I4
I6
I8
Ligand
No
No
No
No
Protein
Yes
Yes
Yes
Yes

Pocket alignment
Uniprot sequence:RVIGRGSYAKVLLYAMKVVWVQTEKHVFEQASPFLVGLHSCFFVIEYVNGGDLMFHMQRYLHERGIIYRDLKLDNVLLLTDYGMC
Sequence structure:RVIGRGSYAKVLLYAMKVVWVQTEKHVFEQASPFLVGLHSCFFVIEYVNGGDLMFHMQRYLHERGIIYRDLKLDNVLLLTDYGMC