Neurotrophic tyrosine kinase, receptor, type 1
Kinase structure
Kinase:NTRK1 (TRKA)
Family:Trk
Group:TK
Species:HUMAN
IUPHAR/BPS ID:1817
PDB:4GT5
sc-PDB:
KIDFamMap:Search
Release date:2012-09-26
PubMed: 22992069
Chain:A
(Alternate) Model:B
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The orthosteric binding pocket


More entries for 4GT5
4GT5Alternative model: AChain: A


Structural information
DFG conformation:out
αC-helix conformation:in
G-rich loop angle (distance):62.6° (19.5Å)
G-rich loop rotation:53°
Quality Score:7.9
Resolution:2.4 Å
Missing Residues:0
Missing Atoms:13
Ligand binding mode
Waters
Cluster
I9
Ligand
No
Protein
Yes

Pocket alignment
Uniprot sequence:WELGEGAFGKVFLVAVKALDFQREAELLTMLQQHIVRFFGVLMVFEYMRHGDLNRFLRSYLAGLHFVHRDLATRNCLVIGDFGMS
Sequence structure:WELGEGAFGKVFLVAVKALDFQREAELLTMLQQHIVRFFGVLMVFEYMRHGDLNRFLRSYLAGLHFVHRDLATRNCLVIGDFGMS