Version: 3.2
Updated: 24-Dec-2025
Calcium/calmodulin-dependent serine protein kinase (MAGUK family)
Kinase structure
Kinase:CASK
Family:CASK
Group:CAMK
Species:HUMAN
IUPHAR/BPS ID:1959
PDB:3TAC
sc-PDB:
KIDFamMap:Search
Release date:2011-10-12
PubMed: 21855798
Chain:A
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The orthosteric binding pocket
Structural information
DFG conformation:in
αC-helix conformation:in
G-rich loop angle (distance):65.4° (19.9Å)
G-rich loop rotation:46.7°
Quality Score:9.4
Resolution:2.2 Å
Missing Residues:0
Missing Atoms:6

Pocket alignment
Uniprot sequence:EVIGKGPFSVVRRFAVKIVDLKREASICHMLKPHIVELLETYMVFEFMDGADLCFEIVKYCHDNNIIHRDVKPHCVLLLGGFGVA
Sequence structure:EVIGKGPFSVVRRFAVKIVDLKREASICHMLKPHIVELLETYMVFEFMDGADLCFEIVKYCHDNNIIHRDVKPHCVLLLGGFGVA