Calcium/calmodulin-dependent serine protein kinase (MAGUK family)
Kinase structure
Kinase:CASK
Family:CASK
Group:CAMK
Species:HUMAN
IUPHAR/BPS ID:1959
PDB:3MFT
sc-PDB:
KIDFamMap:Search
Release date:2010-04-28
PubMed: 20424264
Chain:A
(Alternate) Model:A
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The orthosteric binding pocket


More entries for 3MFT
3MFTAlternative model: BChain: A


Structural information
DFG conformation:in
αC-helix conformation:in
G-rich loop angle (distance):56.6° (17.2Å)
G-rich loop rotation:58°
Quality Score:8
Resolution:2.2 Å
Missing Residues:0
Missing Atoms:0
Ligand binding mode
Waters
Cluster
I1
I4
I5
Ligand
No
No
No
Protein
Yes
Yes
Yes

Pocket alignment
Uniprot sequence:EVIGKGPFSVVRRFAVKIVDLKREASICHMLKPHIVELLETYMVFEFMDGADLCFEIVKYCHDNNIIHRDVKPHCVLLLGGFGVA
Sequence structure:EVIGKGAFSVVRRFAVKIVDLKREASICHMLKPHIVELLETYMVFEFMDGADLCFEIVKYCHDNNIIHRDVKPENVLLLGDFGVA