Cyclin-dependent kinase 2
Kinase structure
Kinase:CDK2
Family:CDK
Group:CMGC
Species:HUMAN
IUPHAR/BPS ID:1973
PDB:1PXP
sc-PDB:
KIDFamMap:Search
Release date:2004-04-13
PubMed: 15027857
Chain:A
(Alternate) Model:B
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The orthosteric binding pocket


More entries for 1PXP
1PXPAlternative model: AChain: A


Structural information
DFG conformation:in
αC-helix conformation:out
G-rich loop angle (distance):46.7° (13.5Å)
G-rich loop rotation:68.6°
Quality Score:8
Resolution:2.3 Å
Missing Residues:0
Missing Atoms:0
Ligand binding mode
Waters
Cluster
I2
I3
I5
I6
I7
Ligand
No
No
No
No
No
Protein
Yes
Yes
Yes
No
Yes

Pocket alignment
Uniprot sequence:EKIGEGTYGVVYKVALKKITAIREISLLKELNPNIVKLLDVYLVFEFLH-QDLKKFMDAFCHSHRVLHRDLKPQNLLILADFGLA
Sequence structure:EKIGEGTYGVVYKVALKKITAIREISLLKELNPNIVKLLDVYLVFEFLH_QDLKKFMDAFCHSHRVLHRDLKPQNLLILADFGLA