Version: 3.2
Updated: 29-Oct-2025
Cyclin-dependent kinase 2
Kinase structure
Kinase:CDK2
Family:CDK
Group:CMGC
Species:HUMAN
IUPHAR/BPS ID:1973
PDB:1OKV
sc-PDB:
KIDFamMap:Search
Release date:2003-12-11
PubMed: 14656438
Chain:C
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The orthosteric binding pocket


More entries for 1OKV
1OKVChain: A


Structural information
DFG conformation:in
αC-helix conformation:in
G-rich loop angle (distance):56° (16.2Å)
G-rich loop rotation:91.2°
Quality Score:8
Resolution:2.4 Å
Missing Residues:0
Missing Atoms:0
Ligand binding mode
Waters
Cluster
I1
I3
I5
I6
I7
I10
Ligand
No
No
No
No
No
No
Protein
Yes
Yes
Yes
Yes
Yes
Yes

Pocket alignment
Uniprot sequence:EKIGEGTYGVVYKVALKKITAIREISLLKELNPNIVKLLDVYLVFEFLH-QDLKKFMDAFCHSHRVLHRDLKPQNLLILADFGLA
Sequence structure:EKIGEGTYGVVYKVALKKITAIREISLLKELNPNIVKLLDVYLVFEFLH_QDLKKFMDAFCHSHRVLHRDLKPQNLLILADFGLA