Cyclin-dependent kinase 2
Kinase structure
Kinase:CDK2
Family:CDK
Group:CMGC
Species:HUMAN
IUPHAR/BPS ID:1973
PDB:1F5Q
sc-PDB:
KIDFamMap:Search
Release date:2000-12-27
PubMed: 10856233
Chain:A
(Alternate) Model:A
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The orthosteric binding pocket


More entries for 1F5Q
1F5QAlternative model: AChain: C
1F5QAlternative model: BChain: A
1F5QAlternative model: BChain: C


Structural information
DFG conformation:in
αC-helix conformation:in
G-rich loop angle (distance):66.9° (19.2Å)
G-rich loop rotation:62.6°
Quality Score:8.5
Resolution:2.5 Å
Missing Residues:2
Missing Atoms:7
Ligand binding mode
Waters
Cluster
I4
I5
Ligand
No
No
Protein
Yes
Yes

Pocket alignment
Uniprot sequence:EKIGEGTYGVVYKVALKKITAIREISLLKELNPNIVKLLDVYLVFEFLH-QDLKKFMDAFCHSHRVLHRDLKPQNLLILADFGLA
Sequence structure:EK__EGTYGVVYKVALKKITAIREISLLKELNPNIVKLLDVYLVFEFLH_QDLKKFMDAFCHSHRVLHRDLKPQNLLILADFGLA