Cyclin-dependent kinase 2
Kinase structure
Kinase:CDK2
Family:CDK
Group:CMGC
Species:HUMAN
IUPHAR/BPS ID:1973
PDB:2R3I
sc-PDB:
KIDFamMap:Search
Release date:2008-01-22
PubMed: 17937404
Chain:A
(Alternate) Model:C
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The orthosteric binding pocket


More entries for 2R3I
2R3IAlternative model: AChain: A
2R3IAlternative model: BChain: A


Structural information
DFG conformation:in
αC-helix conformation:out
G-rich loop angle (distance):50.1° (14.3Å)
G-rich loop rotation:72.5°
Quality Score:6.4
Resolution:1.28 Å
Missing Residues:4
Missing Atoms:0
Ligand binding mode
Waters
Cluster
I1
I4
I5
Ligand
No
No
No
Protein
No
No
Yes

Pocket alignment
Uniprot sequence:EKIGEGTYGVVYKVALKKITAIREISLLKELNPNIVKLLDVYLVFEFLH-QDLKKFMDAFCHSHRVLHRDLKPQNLLILADFGLA
Sequence structure:EKIGEGTYGVVYKVA_KKITAIREI_LLKELNPNIVKLLDVYLVFEFLH_QDLKKFMDAFCHSHRVLH_DLKP_NLLILADFGLA