Cyclin-dependent kinase 2
Kinase structure
Kinase:CDK2
Family:CDK
Group:CMGC
Species:HUMAN
IUPHAR/BPS ID:1973
PDB:2WHB
sc-PDB:
KIDFamMap:Search
Release date:2009-06-09
PubMed: 19472269
Chain:C
(Alternate) Model:B
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The orthosteric binding pocket


More entries for 2WHB
2WHBAlternative model: AChain: A
2WHBAlternative model: AChain: C
2WHBAlternative model: BChain: A


Structural information
DFG conformation:in
αC-helix conformation:in
G-rich loop angle (distance):52.4° (15.4Å)
G-rich loop rotation:81.9°
Quality Score:8
Resolution:2.9 Å
Missing Residues:0
Missing Atoms:0
Ligand binding mode
Waters
Cluster
I2
I3
Ligand
No
No
Protein
Yes
Yes

Pocket alignment
Uniprot sequence:EKIGEGTYGVVYKVALKKITAIREISLLKELNPNIVKLLDVYLVFEFLH-QDLKKFMDAFCHSHRVLHRDLKPQNLLILADFGLA
Sequence structure:EKIGEGTYGVVYKVALKKITAIREISLLKELNPNIVKLLDVYLVFEFLH_QDLKKFMDAFCHSHRVLHRDLKPQNLLILADFGLA