Version: 3.2
Updated: 29-Oct-2025
Checkpoint kinase 2
Kinase structure
Kinase:CHEK2 (CHK2)
Family:RAD53
Group:CAMK
Species:HUMAN
IUPHAR/BPS ID:1988
PDB:3I6W
sc-PDB:
KIDFamMap:Search
Release date:2009-11-10
PubMed: 19782031
Chain:G
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The orthosteric binding pocket


More entries for 3I6W
3I6WChain: A
3I6WChain: B
3I6WChain: C
3I6WChain: D
3I6WChain: E
3I6WChain: F
3I6WChain: H


Structural information
DFG conformation:in
αC-helix conformation:out
G-rich loop angle (distance):-
G-rich loop rotation:-
Quality Score:6.2
Resolution:3.25 Å
Missing Residues:8
Missing Atoms:6

Pocket alignment
Uniprot sequence:KTLGSGACGEVKLVAIKIINVETEIEILKKLNPCIIKIKNFYIVLELMEGGELFDKVVGYLHENGIIHRDLKPENVLLITDFGHS
Sequence structure:KTLG_____EVKLVAIRIINVETEIEILKKLNPCIIKIKNFYIVLELMEGGELFDKVVGYLHENGIIHRDLKPENVLLITDF___