Version: 3.2
Updated: 29-Oct-2025
Death-associated protein kinase 1
Kinase structure
Kinase:DAPK1
Family:DAPK
Group:CAMK
Species:HUMAN
IUPHAR/BPS ID:2002
PDB:4UV0
sc-PDB:
KIDFamMap:Search
Release date:2015-08-12
Chain:A
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The orthosteric binding pocket
Structural information
DFG conformation:in
αC-helix conformation:in
G-rich loop angle (distance):57.8° (17.5Å)
G-rich loop rotation:43°
Quality Score:9
Resolution:2.49 Å
Missing Residues:0
Missing Atoms:10
Ligand binding mode
Waters
Cluster
I2
Ligand
No
Protein
No

Pocket alignment
Uniprot sequence:EELGSGQFAVVKKYAAKFIDIEREVSILKEIQPNVITLHEVILILELVAGGELFDFLAEYLHSLQIAHFDLKPENIMLIIDFGLA
Sequence structure:EELGSGQFAVVKKYAAKFIDIEREVSILKEIQPNVITLHEVILILELVAGGELFDFLAEYLHSLQIAHFDLKPENIMLIIDFGLA