Version: 3.2
Updated: 29-Oct-2025
Death-associated protein kinase 1
Kinase structure
Kinase:DAPK1
Family:DAPK
Group:CAMK
Species:HUMAN
IUPHAR/BPS ID:2002
PDB:4PF4
sc-PDB:
KIDFamMap:Search
Release date:2014-05-14
Chain:A
(Alternate) Model:B
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The orthosteric binding pocket


More entries for 4PF4
4PF4Alternative model: AChain: A


Structural information
DFG conformation:in
αC-helix conformation:in
G-rich loop angle (distance):54° (16Å)
G-rich loop rotation:42.8°
Quality Score:9.6
Resolution:1.13 Å
Missing Residues:0
Missing Atoms:4
Ligand binding mode
Waters
Cluster
I1
I3
I4
I5
I7
Ligand
No
No
No
No
No
Protein
Yes
Yes
Yes
Yes
Yes

Pocket alignment
Uniprot sequence:EELGSGQFAVVKKYAAKFIDIEREVSILKEIQPNVITLHEVILILELVAGGELFDFLAEYLHSLQIAHFDLKPENIMLIIDFGLA
Sequence structure:EELGSGQFAVVKKYAAKFIDIEREVSILKEIQPNVITLHEVILILELVAGGELFDFLAEYLHSLQIAHFDLKPENIMLIIDFGLA