Version: 3.2
Updated: 29-Oct-2025
Death-associated protein kinase 1
Kinase structure
Kinase:DAPK1
Family:DAPK
Group:CAMK
Species:HUMAN
IUPHAR/BPS ID:2002
PDB:2Y4P
sc-PDB:
KIDFamMap:Search
Release date:2012-01-18
Chain:C
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The orthosteric binding pocket


More entries for 2Y4P
2Y4PChain: A
2Y4PChain: B
2Y4PChain: D


Structural information
DFG conformation:in
αC-helix conformation:in
G-rich loop angle (distance):55.7° (16.5Å)
G-rich loop rotation:48.6°
Quality Score:9.2
Resolution:2.65 Å
Missing Residues:0
Missing Atoms:8
Ligand binding mode
Waters
Cluster
I2
I4
I5
Ligand
No
No
No
Protein
Yes
Yes
Yes

Pocket alignment
Uniprot sequence:EELGSGQFAVVKKYAAKFIDIEREVSILKEIQPNVITLHEVILILELVAGGELFDFLAEYLHSLQIAHFDLKPENIMLIIDFGLA
Sequence structure:EELGSGQFAVVKKYAAKFIDIEREVSILKEIQPNVITLHEVILILELVAGGELFDFLAEYLHSLQIAHFDLKPENIMLIIDFGLA