Version: 3.2
Updated: 01-Nov-2025
Ribosomal protein S6 kinase polypeptide 3 (2nd domain)
Kinase structure
Kinase:Rps6ka3-b (RSK2-b)
Family:RSKb
Group:CAMK
Species:MOUSE
PDB:2QR8
sc-PDB:
KIDFamMap:Search
Release date:2007-12-11
PubMed: 18084304
Chain:A
(Alternate) Model:B
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The orthosteric binding pocket


More entries for 2QR8
2QR8Alternative model: AChain: A


Structural information
DFG conformation:in
αC-helix conformation:in
G-rich loop angle (distance):56.5° (17.2Å)
G-rich loop rotation:25.9°
Quality Score:8
Resolution:2 Å
Missing Residues:0
Missing Atoms:0
Ligand binding mode
Waters
Cluster
I4
Ligand
No
Protein
Yes

Pocket alignment
Uniprot sequence:EDIGVGSYSVCKRFAVKIIDPTEEIEILLRYGPNIITLKDVYVVTELMKGGELLDKILRYLHAQGVVHRDLKPSNILYICDFGFA
Sequence structure:EDIGVGSYSVCKRFAVKIIDPTEEIEILLRYGPNIITLKDVYVVTELMKGGELLDKILRYLHAQGVVHRDLKPSNILYICDFGFA