Version: 3.2
Updated: 24-Dec-2025
Eukaryotic translation initiation factor 2 alpha kinase 3
Kinase structure
Kinase:Eif2ak3 (PEK)
Family:PEK
Group:Other
Species:MOUSE
PDB:3QD2
sc-PDB:
KIDFamMap:Search
Release date:2011-04-27
PubMed: 21543844
Chain:B
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The orthosteric binding pocket
Structural information
DFG conformation:out
αC-helix conformation:in
G-rich loop angle (distance):31.5° (19.9Å)
G-rich loop rotation:104.3°
Quality Score:3.2
Resolution:2.81 Å
Missing Residues:2
Missing Atoms:0
Ligand binding mode
Waters
Cluster
I11
Ligand
No
Protein
Yes

Pocket alignment
Uniprot sequence:QCMGRGGFGVVFEYAIKRIKVMREVKALAKLEPGIVRYFNAPKVYLYIQ-MQLCRKENLFLHSKGLMHRDLKPSNIFFVGDFGLV
Sequence structure:GRGFGVVFEAKNKKRIRLPVMREVKALAKLEHGIVRYFNAWKWQEEMDEPKVYLYIQMQ__HSKGLMHRDLKPSNIFFDFGLVTA