Receptor-interacting serine-threonine kinase 3
Kinase structure
Kinase:Ripk3 (RIPK3)
Family:RIPK
Group:TKL
Species:MOUSE
PDB:4M66
sc-PDB:
KIDFamMap:Search
Release date:2013-10-16
PubMed: 24095729
Chain:A
(Alternate) Model:B
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The orthosteric binding pocket


More entries for 4M66
4M66Alternative model: AChain: A
4M66Alternative model: AChain: B
4M66Alternative model: BChain: B


Structural information
DFG conformation:in
αC-helix conformation:in
G-rich loop angle (distance):52.4° (16.1Å)
G-rich loop rotation:41.1°
Quality Score:8
Resolution:2.4 Å
Missing Residues:0
Missing Atoms:0
Ligand binding mode
Waters
Cluster
I2
I4
I5
Ligand
No
No
No
Protein
Yes
Yes
Yes

Pocket alignment
Uniprot sequence:EFVGKGGFGVVFRVAVKIVKISWEVKAMVNLRENVLLLLGVALVTRFMENGSLAGLLQPHSLNPPLLHRDLKPSNILLLADFGLS
Sequence structure:EFVGKGGFGVVFRVAVKIVKISWEVKAMVNLRENVLLLLGVALVTRFMENGSLAGLLQPHSLDPPLLHRDLKPSNILLLADFGLS