Version: 3.2
Updated: 29-Oct-2025
Protein kinase, cAMP dependent, catalytic, alpha
Kinase structure
Kinase:Prkaca (PKACa)
Family:PKA
Group:AGC
Species:MOUSE
PDB:4X6Q
sc-PDB:
KIDFamMap:Search
Release date:2015-07-22
PubMed: 26278174
Chain:C
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The orthosteric binding pocket
Structural information
DFG conformation:in
αC-helix conformation:in
G-rich loop angle (distance):49.6° (15.3Å)
G-rich loop rotation:43.7°
Quality Score:8
Resolution:2.52 Å
Missing Residues:0
Missing Atoms:0

Pocket alignment
Uniprot sequence:KTLGTGSFGRVMLYAMKILHTLNEKRILQAVNPFLVKLEFSYMVMEYVAGGEMFSHLRRYLHSLDLIYRDLKPENLLIVTDFGFA
Sequence structure:KTLGTGSFGRVMLYAMKILHTLNEKRILQAVNPFLVKLEFSYMVMEYVAGGEMFSHLRRYLHSLDLIYRDLKPENLLIVTDFGFA