Version: 3.2
Updated: 29-Oct-2025
Protein kinase, cAMP dependent, catalytic, alpha
Kinase structure
Kinase:Prkaca (PKACa)
Family:PKA
Group:AGC
Species:MOUSE
PDB:4NTS
sc-PDB:
KIDFamMap:Search
Release date:2014-10-15
PubMed: 25077557
Chain:A
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The orthosteric binding pocket


More entries for 4NTS
4NTSChain: B


Structural information
DFG conformation:in
αC-helix conformation:in
G-rich loop angle (distance):70.7° (21.9Å)
G-rich loop rotation:51.4°
Quality Score:8.1
Resolution:2.9 Å
Missing Residues:0
Missing Atoms:19

Pocket alignment
Uniprot sequence:KTLGTGSFGRVMLYAMKILHTLNEKRILQAVNPFLVKLEFSYMVMEYVAGGEMFSHLRRYLHSLDLIYRDLKPENLLIVTDFGFA
Sequence structure:KTLGTGSFGRVMLYAMKILHTLNEKRILQAVNPFLVKLEFSYMVMEYVAGGEMFSHLRRYLHSLDLIYRDLKPENLLIVTDFGFA