Version: 3.2
Updated: 29-Oct-2025
Protein kinase, cAMP dependent, catalytic, alpha
Kinase structure
Kinase:Prkaca (PKACa)
Family:PKA
Group:AGC
Species:MOUSE
PDB:1APM
sc-PDB:
KIDFamMap:Search
Release date:1993-04-15
PubMed: 15299526
Chain:E
(Alternate) Model:B
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The orthosteric binding pocket


More entries for 1APM
1APMAlternative model: AChain: E


Structural information
DFG conformation:in
αC-helix conformation:in
G-rich loop angle (distance):50.8° (15.7Å)
G-rich loop rotation:63.3°
Quality Score:8.5
Resolution:2 Å
Missing Residues:0
Missing Atoms:15
Ligand binding mode
Waters
Cluster
I1
I4
Ligand
No
No
Protein
Yes
Yes

Pocket alignment
Uniprot sequence:KTLGTGSFGRVMLYAMKILHTLNEKRILQAVNPFLVKLEFSYMVMEYVAGGEMFSHLRRYLHSLDLIYRDLKPENLLIVTDFGFA
Sequence structure:KTLGTGSFGRVMLYAMKILHTLNEKRILQAVNPFLVKLEFSYMVMEYVAGGEMFSHLRRYLHSLDLIYRDLKPENLLIVTDFGFA