Version: 3.2
Updated: 29-Oct-2025
Protein kinase, cAMP dependent, catalytic, alpha
Kinase structure
Kinase:Prkaca (PKACa)
Family:PKA
Group:AGC
Species:MOUSE
PDB:3O7L
sc-PDB:
KIDFamMap:Search
Release date:2010-10-06
PubMed: 20890288
Chain:D
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The orthosteric binding pocket


More entries for 3O7L
3O7LChain: B


Structural information
DFG conformation:in
αC-helix conformation:in
G-rich loop angle (distance):66.2° (20.6Å)
G-rich loop rotation:49.4°
Quality Score:8
Resolution:2.8 Å
Missing Residues:0
Missing Atoms:28
Ligand binding mode
Waters
Cluster
I8
Ligand
No
Protein
No

Pocket alignment
Uniprot sequence:KTLGTGSFGRVMLYAMKILHTLNEKRILQAVNPFLVKLEFSYMVMEYVAGGEMFSHLRRYLHSLDLIYRDLKPENLLIVTDFGFA
Sequence structure:KTLGTGSFGRVMLYAMKILHTLNEKRILQAVNPFLVKLEFSYMVMEYVAGGEMFSHLRRYLHSLDLIYRDLKPENLLIVTDFGFA