Mitogen-activated protein kinase kinase kinase kinase 4
Kinase structure
Kinase:MAP4K4 (HGK)
Family:STE20
Group:STE
Species:HUMAN
IUPHAR/BPS ID:2088
PDB:4U3Z
sc-PDB:
KIDFamMap:Search
Release date:2016-01-06
Chain:A
(Alternate) Model:A
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The orthosteric binding pocket


More entries for 4U3Z
4U3ZAlternative model: AChain: B
4U3ZAlternative model: BChain: A
4U3ZAlternative model: BChain: B


Structural information
DFG conformation:out-like
αC-helix conformation:out
G-rich loop angle (distance):-
G-rich loop rotation:-
Quality Score:5.2
Resolution:2.09 Å
Missing Residues:7
Missing Atoms:0
Ligand binding mode
Waters
Cluster
I2
I5
Ligand
No
No
Protein
No
Yes

Pocket alignment
Uniprot sequence:EVVGNGTYGQVYKAAIKVMEIKLEINMLKKYSRNIATYYGAWLVMEFCGAGSITDLVKNHLHIHHVIHRDIKGQNVLLLVDFGVS
Sequence structure:EVV_______VYKAAIKVMEIKLEINMLKKYSRNIATYYGAWLVMEFCGAGSITDLVKNHLHIHHVIHRDIKGQNVLLLVDFGVS