PDZ binding kinase
Kinase structure
Kinase:PBK
Family:TOPK
Group:Other
Species:HUMAN
IUPHAR/BPS ID:2140
PDB:5J0A
sc-PDB:
KIDFamMap:Search
Release date:2016-09-07
PubMed: 27262437
Chain:A
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The orthosteric binding pocket


More entries for 5J0A
5J0AChain: B


Structural information
DFG conformation:in
αC-helix conformation:out
G-rich loop angle (distance):112.5° (60.3Å)
G-rich loop rotation:67°
Quality Score:4
Resolution:2.74 Å
Missing Residues:0
Missing Atoms:0
Ligand binding mode
Waters
Cluster
I5
Ligand
No
Protein
Yes

Allosteric Ligand
Allosteric ligand:HC4
2D structure of the allostericligand
Pocket alignment
Uniprot sequence:QKLGFGTGVNVYLWAVKKIRLMDEAKILKSLHPNIVGYRAFCLAMEYGGEKSLNDLIEELHQEKKLLHGDIKSSNVVIICDVGVS
Sequence structure:QKLGFGTGVNVYLWAVKKIRLMDEAKILKSLHPNIVGYRAFCLAMEYGGEKSLNDLIEELHQEKKLLHGDIKSSNVVIICDVGVS