Protein kinase N1
Kinase structure
Kinase:PKN1
Family:PKN
Group:AGC
Species:HUMAN
IUPHAR/BPS ID:1520
PDB:4OTH
sc-PDB:
KIDFamMap:Search
Release date:2014-08-27
PubMed: 25111382
Chain:A
(Alternate) Model:A
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The orthosteric binding pocket


More entries for 4OTH
4OTHAlternative model: BChain: A


Structural information
DFG conformation:in
αC-helix conformation:out
G-rich loop angle (distance):56.3° (16.7Å)
G-rich loop rotation:44.6°
Quality Score:8
Resolution:1.8 Å
Missing Residues:0
Missing Atoms:0
Ligand binding mode
Waters
Cluster
I4
I5
Ligand
No
No
Protein
Yes
Yes

Pocket alignment
Uniprot sequence:AVLGRGHFGKVLLFAIKALSLMCEKRILAAVTPFLVNLFGCCFVMEYSAGGDLMLHIHSFLHEHKIVYRDLKLDNLLLIADFGLC
Sequence structure:AVLGRGHFGKVLLFAIKALSLMCEKRILAAVTPFLVNLFGCCFVMEYSAGGDLMLHIHSFLHEHKIVYRDLKLDNLLLIADFGLC