Pim-1 proto-oncogene, serine/threonine kinase
Kinase structure
Kinase:PIM1
Family:PIM
Group:CAMK
Species:HUMAN
IUPHAR/BPS ID:2158
PDB:2BZI
sc-PDB:
KIDFamMap:Search
Release date:2005-12-08
Chain:B
(Alternate) Model:B
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The orthosteric binding pocket


More entries for 2BZI
2BZIAlternative model: AChain: B


Structural information
DFG conformation:in
αC-helix conformation:in
G-rich loop angle (distance):54.1° (16.4Å)
G-rich loop rotation:39°
Quality Score:8
Resolution:1.9 Å
Missing Residues:0
Missing Atoms:0
Ligand binding mode
Waters
Cluster
I1
I5
Ligand
No
No
Protein
Yes
Yes

Pocket alignment
Uniprot sequence:PLLGSGGFGSVYSVAIKHVRVPMEVVLLKKVSSGVIRLLDWVLILERPEVQDLFDFITEHCHNCGVLHRDIKDENILILIDFGSG
Sequence structure:PLLGSGGFGSVYSVAIKHVRVPMEVVLLKKVSSGVIRLLDWVLILERPEVQDLFDFITEHCHNCGVLHRDIKDENILILIDFGSG