Epidermal growth factor receptor
Kinase structure
Kinase:EGFR
Family:EGFR
Group:TK
Species:HUMAN
IUPHAR/BPS ID:1797
PDB:4ZJV
sc-PDB:
KIDFamMap:Search
Release date:2015-08-12
PubMed: 26280531
Chain:A
(Alternate) Model:A
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The orthosteric binding pocket


More entries for 4ZJV
4ZJVAlternative model: AChain: B
4ZJVAlternative model: BChain: A
4ZJVAlternative model: BChain: B


Structural information
DFG conformation:out
αC-helix conformation:in
G-rich loop angle (distance):49.5° (15.5Å)
G-rich loop rotation:42.6°
Quality Score:8
Resolution:2.7 Å
Missing Residues:0
Missing Atoms:0

Pocket alignment
Uniprot sequence:KVLGSGAFGTVYKVAIKELEILDEAYVMASVDPHVCRLLGIQLITQLMPFGCLLDYVREYLEDRRLVHRDLAARNVLVITDFGLA
Sequence structure:KVLGSGAFGTVYKVAIKELEILDEAYVMASVDPHVCRLLGIQLITQLMPFGCLLDYVREYLEDRRLVHRDLAARNVLVITDFGLA