WNK lysine deficient protein kinase 3
Kinase structure
Kinase:WNK3 (Wnk3)
Family:WNK
Group:Other
Species:HUMAN
IUPHAR/BPS ID:2282
PDB:5O2C
sc-PDB:
KIDFamMap:Search
Release date:2017-06-28
Chain:A
Click to open a 3D viewer
The orthosteric binding pocket
Structural information
DFG conformation:in
αC-helix conformation:out
G-rich loop angle (distance):54.5° (16Å)
G-rich loop rotation:36.2°
Quality Score:8
Resolution:2.4 Å
Missing Residues:0
Missing Atoms:0
Ligand binding mode
Waters
Cluster
I1
I3
Ligand
No
No
Protein
Yes
Yes

Pocket alignment
Uniprot sequence:IELGRGAFKTVYKVAWCELRFKEEAEMLKGLQPNIVRFYDSVLVTELMTSGTLKTYLKRHTRTPPIIHRDLKCDNIFIIGDLGLA
Sequence structure:IELGRGAFKTVYKVAWCELRFKEEAEMLKGLQPNIVRFYDSVLVTELMTSGTLKTYLKRHTRTPPIIHRDLKCDNIFIIGDLGLA