Epidermal growth factor receptor
Kinase structure
Kinase:EGFR
Family:EGFR
Group:TK
Species:HUMAN
IUPHAR/BPS ID:1797
PDB:2GS6
sc-PDB:
KIDFamMap:Search
Release date:2006-06-20
PubMed: 16777603
Chain:A
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The orthosteric binding pocket
Structural information
DFG conformation:in
αC-helix conformation:in
G-rich loop angle (distance):62° (19.2Å)
G-rich loop rotation:29°
Quality Score:9.4
Resolution:2.6 Å
Missing Residues:0
Missing Atoms:6

Pocket alignment
Uniprot sequence:KVLGSGAFGTVYKVAIKELEILDEAYVMASVDPHVCRLLGIQLITQLMPFGCLLDYVREYLEDRRLVHRDLAARNVLVITDFGLA
Sequence structure:KVLGSGAFGTVYKVAIKELEILDEAYVMASVDPHVCRLLGIQLITQLMPFGCLLDYVREYLEDRRLVHRDLAARNVLVITDFGLA