Epidermal growth factor receptor
Kinase structure
Kinase:EGFR
Family:EGFR
Group:TK
Species:HUMAN
IUPHAR/BPS ID:1797
PDB:4I20
sc-PDB:
KIDFamMap:Search
Release date:2013-01-16
PubMed: 23273428
Chain:A
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The orthosteric binding pocket
Structural information
DFG conformation:out
αC-helix conformation:in
G-rich loop angle (distance):45.2° (14Å)
G-rich loop rotation:39.9°
Quality Score:8
Resolution:3.34 Å
Missing Residues:0
Missing Atoms:0

Pocket alignment
Uniprot sequence:KVLGSGAFGTVYKVAIKELEILDEAYVMASVDPHVCRLLGIQLITQLMPFGCLLDYVREYLEDRRLVHRDLAARNVLVITDFGLA
Sequence structure:KVLGSGAFGTVYKVAIKELEILDEAYVMASVDPHVCRLLGIQLITQLMPFGCLLDYVREYLEDRRLVHRDLAARNVLVITDFGRA