PDB-code
| Kinase structure | |
| Kinase: | EGFR |
| Family: | EGFR |
| Group: | TK |
| Species: | HUMAN |
| IUPHAR/BPS ID: | 1797 |
| PDB: | 2RFE |
| sc-PDB: | |
| KIDFamMap: | Search |
| Release date: | 2007-12-04 |
| PubMed: | 18046415 |
| Chain: | B |
| More entries for 2RFE | |||
| 2RFE | Chain: | A | |
| 2RFE | Chain: | C | |
| 2RFE | Chain: | D | |
| Structural information | |
| DFG conformation: | in |
| αC-helix conformation: | out |
| G-rich loop angle (distance): | 55° (16.4Å) |
| G-rich loop rotation: | 39.1° |
| Quality Score: | 8.7 |
| Resolution: | 2.9 Å |
| Missing Residues: | 0 |
| Missing Atoms: | 13 |
| Ligand binding mode | ||||
| Waters | ||||
| Cluster I5 | Ligand No | Protein Yes | ||
| Pocket alignment | |
| Uniprot sequence: | KVLGSGAFGTVYKVAIKELEILDEAYVMASVDPHVCRLLGIQLITQLMPFGCLLDYVREYLEDRRLVHRDLAARNVLVITDFGLA |
| Sequence structure: | KVLGSGAFGTVYKVAIKELEILDEAYVMASVDPHVCRLLGIQLITQLMPFGCLLDYVREYLEDRRLVHRDLAARNVLVITDFGLA |
