Cyclin-dependent kinase 2
Kinase structure
Kinase:CDK2
Family:CDK
Group:CMGC
Species:HUMAN
IUPHAR/BPS ID:1973
PDB:5OSJ
sc-PDB:
KIDFamMap:Search
Release date:2018-03-14
PubMed: 29480525
Chain:A
(Alternate) Model:A
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The orthosteric binding pocket


More entries for 5OSJ
5OSJAlternative model: BChain: A


Structural information
DFG conformation:in
αC-helix conformation:out
G-rich loop angle (distance):53° (15.2Å)
G-rich loop rotation:68.9°
Quality Score:8.3
Resolution:1.83 Å
Missing Residues:0
Missing Atoms:17
Ligand binding mode
Waters
Cluster
I1
I2
I3
I4
I5
I6
I7
Ligand
No
No
No
No
No
No
No
Protein
Yes
No
No
No
Yes
No
Yes

Allosteric Ligand
Allosteric ligand:AAK
2D structure of the allostericligand
Pocket alignment
Uniprot sequence:EKIGEGTYGVVYKVALKKITAIREISLLKELNPNIVKLLDVYLVFEFLH-QDLKKFMDAFCHSHRVLHRDLKPQNLLILADFGLA
Sequence structure:EKIGEGTYGVVYKVALKKITAIREISLLKELNPNIVKLLDVYLVFEFLH_QDLKKFMDAFCHSHRVLHRDLKPQNLLILADFGLA